Enemies
- his archenemy is the Avenger, Captain America
- Spider man, was Red Skull's archenemy before Captain America
- All avengers
- S.H.I.E.L.D.
- Bucky
Allies
- Hitler
- George John Maxon, a Nazi spy, and a agent for Red Skull
- Sinthea Schmidt, the daughter of Red Skull
- All Nazi party members